Extensive primary cutaneous fusariosis in a patient with burns: A case report and review of the literature

J Mycol Med. 2024 Mar;34(1):101450. doi: 10.1016/j.mycmed.2023.101450. Epub 2023 Nov 7.

Abstract

Background: Fusarium species can cause a broad spectrum of human infections, ranging from superficial and locally invasive to disseminated, depending on the immune status of the host and portal of entry. Although several cases of cutaneous fusariosis in burn victims have been reported, molecular identification for pathogen recognition has been used only in a few cases.

Case description: In this report, we describe an uncommon case of extensive primary cutaneous fusariosis caused by Fusarium keratoplasticum in a patient who sustained injuries during stubble burning.

Findings: A review of cases of cutaneous fusariosis in burn victims revealed that this uncommon infection could be lethal, and treatment strategies should focus on both surgical debridement and the initiation of systemic antifungal therapy. Furthermore, because skin defects can serve as a portal of entry for Fusarium species in burn victims, early and aggressive treatment is crucial to prevent serious consequences.

Keywords: Burn; Fusariosis; Invasive fungal infection; Stubble burning.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Burns* / complications
  • Fusariosis* / diagnosis
  • Fusariosis* / drug therapy
  • Fusarium*
  • Humans

Substances

  • Antifungal Agents