Objective: Stereotactic radiosurgery is a therapeutic modality for cavernomas that is associated with certain adverse effects, such as perilesional edema. In this study, we aimed to estimate the presentation of perilesional edema using imaging techniques, considering its location, proximity to major venous and arterial structures, size, depth, and eloquent location.
Patients and methods: The radiographic evaluation included their sizes, localization of the lobes, whether they were in the deep or superficial regions, eloquent areas, and their proximity to the major arteries and venous sinuses.
Results: As the size increased, the time to edema increased at the same rate (r=0.972, p=0.001). We determined that the duration of edema increases as it attaches to the great venous structures, and edema occurs over a longer time (r=-0.761, p=0.001). Cavernomas >13 mm had a high probability of causing edema (p=0.0014). Edema occurred with a high probability in patients with an arterial distance <5.69 mm and a venous/arterial distance ratio >8.93 (specificity 100%, selectivity 98.2%).
Conclusions: When recommending stereostatic radiosurgery treatment, the possibility of edema formation should be calculated based on the location, size, and proximity of the cavernoma to the vascular structures, and the choice of treatment should be made accordingly.