Relationship of the SITLESS intervention on medication use in community-dwelling older adults: an exploratory study

Front Public Health. 2023 Nov 16:11:1238842. doi: 10.3389/fpubh.2023.1238842. eCollection 2023.

Abstract

Background: Sedentary behavior (SB) and physical activity (PA) interventions in older adults can improve health outcomes. Problems related with aging include prevalent comorbidity, multiple non-communicable diseases, complaints, and resulting polypharmacy. This manuscript examines the relationship between an intervention aiming at reducing SB on medication patterns.

Method: This manuscript presents a local sub-analysis of the SITLESS trial data on medication use. SITLESS was an exercise referral scheme (ERS) enhanced by self-management strategies (SMS) to reduce SB in community-dwelling older adults. We analyzed data from the ERS + SMS, ERS and usual care (UC) groups. Patient medication records were available at baseline and at the end of the intervention (4-month period) and were analyzed to explore the effect of SITLESS on medication patterns of use.

Result: A sample of 75 participants was analyzed, mostly older overweight women with poor body composition scores and mobility limitations. There was a significant reduction of 1.6 medicines (SD = 2.7) in the ERS group (p < 0.01), but not in the UC or ERS + SMS groups. Differences were more evident in medicines used for short periods of time.

Conclusion: The findings suggest that an exercise-based program enhanced by SMS to reduce SB might influence medication use for acute conditions but there is a need to further investigate effects on long-term medicine use in older adults.

Keywords: intervention; medication use; older adults; physical activity; primary health care; sedentary behavior.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aging
  • Clinical Trials as Topic
  • Exercise*
  • Female
  • Humans
  • Independent Living*
  • Male
  • Sedentary Behavior

Grants and funding

The SITLESS project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement number 634270. RV is a PhD scholar of Fundação para a Ciência e Tecnologia, I.P. (FCT), Ministério da Ciência e Tecnologia, Portugal (Grant number: SFRH/BD/13164/2022).