Rare association between giant-cell aortitis and giant-cell aortic valvulitis

Georgina Del Cisne Jadán Luzuriaga; Ricardo Ribeiro Dias; José Augusto Duncan Santiago; Vagner Madrini; Walther Yoshiharu Ishikawa; Fabio Fernandes; Vera Demarchi Aiello

doi:10.4322/acr.2023.449

Rare association between giant-cell aortitis and giant-cell aortic valvulitis

Autops Case Rep. 2023 Oct 23:13:e2023449. doi: 10.4322/acr.2023.449. eCollection 2023.

Authors

Georgina Del Cisne Jadán Luzuriaga¹, Ricardo Ribeiro Dias², José Augusto Duncan Santiago², Vagner Madrini¹, Walther Yoshiharu Ishikawa³, Fabio Fernandes¹, Vera Demarchi Aiello⁴

Affiliations

¹ Universidade de São Paulo, Faculdade de Medicina, Instituto do Coração, Departamento de Miocardiopatias e Doenças da Aorta, São Paulo, SP, Brasil.
² Universidade de São Paulo, Faculdade de Medicina, Instituto do Coração, Departamento de Cirurgia Cardiovascular, São Paulo, SP, Brasil.
³ Universidade de São Paulo, Faculdade de Medicina, Instituto do Coração, Departamento de Imagem Cardiovascular, São Paulo, SP, Brasil.
⁴ Universidade de São Paulo, Faculdade de Medicina, Instituto do Coração, Departamento de Anatomia Patológica, São Paulo, SP, Brasil.

Abstract

Giant cell arteritis (GCA) is a type of chronic vasculitis that affects medium and large-caliber arteries, frequently related to aortic involvement and, consequently, to aneurysm formation. However, associated valvulitis with giant cells is uncommon. We describe the case of a 50-year-old female patient with aortic aneurysm and valvular insufficiency, whose anatomopathological examination revealed giant-cell aortic valvulitis associated with giant cell aortitis.

Keywords: Aorta, Thoracic; Aortic Aneurysm; Aortic Diseases; Aortic Valve; Aortic Valve Insufficiency.

Publication types

Case Reports