A Comparative Histological Study of Gingival Depigmentation by 808 and 445 nm Diode Lasers

Seyed Masoud Mojahedi Nasab; Matthias Frentzen; Somayeh Rahmani; Fahimeh Anbari; Saranaz Azari-Marhabi; Jörg Meister; Deniz Mojahedi Nasab

doi:10.34172/jlms.2023.48

A Comparative Histological Study of Gingival Depigmentation by 808 and 445 nm Diode Lasers

J Lasers Med Sci. 2023 Oct 25:14:e48. doi: 10.34172/jlms.2023.48. eCollection 2023.

Authors

Seyed Masoud Mojahedi Nasab^{1

2}, Matthias Frentzen^{1

2}, Somayeh Rahmani³, Fahimeh Anbari³, Saranaz Azari-Marhabi⁴, Jörg Meister^{1

2

4}, Deniz Mojahedi Nasab⁵

Affiliations

¹ Department of Periodontology, Operative and Preventive Dentistry, Dental Faculty University on Bonn. Welschnonnensytasse 17, 53111 Bonn, Germany.
² Center of Applied Medical Laser Research and Biomedical Optics (AMLaReBO), Univerity of Bonn, Germany.
³ Department of oral and Maxillofacial Medicine, Shahid Beheshti Dental School, Tehran, Iran.
⁴ Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁵ Biology Department of Azad University, Tehran Iran.

Abstract

Introduction: Using lasers in melanin depigmentation is one of the main fields of interest for dental practitioners and patients. However, it is important to know what would happen inside the tissue and how the cells would interact inside the tissue with a laser. Methods: In this study, we used both wavelengths of 445 nm and 808 nm on sheep gingiva to find out the effects and side effects of these diode lasers while using them for gingival depigmentation. Results: After microscopic evaluation, we concluded that 808 nm and 445 nm lasers with a power of 1 W are safe enough to use in the depigmentation of gingiva, and both lasers are highly effective in melanin pigments which are located in basal membrane. Conclusion: The 445 nm blue laser produced a less thermal effect, which means it is safer to be used in gingival hyperpigmentation than a diode laser.

Keywords: Blue laser; Melanin depigmentation; Microscopic evaluation; Thermal effects.