Sociodemographic Factors Related to Adverse Donor Reactions in Shenzhen

Int J Gen Med. 2023 Nov 23:16:5493-5499. doi: 10.2147/IJGM.S443682. eCollection 2023.

Abstract

Background: The adverse donor reaction (ADR) means the uncomfortable feeling felt by blood donors during the whole process of blood donation, which can affect the blood donation behavior of blood donors. So, it is very necessary for blood centers to monitor and prevent it.

Methods: Data about ADRs in Shenzhen Blood Center from January 2018 to December 2022 were collected, and correlation analysis was conducted using SPSS 24.0 software.

Results: From January 2018 to December 2022, a total of 1265 ADRs occurred in 642,767 blood donations in Shenzhen Blood Center, with an incidence of 0.20%. Most of the ADRs were mild and occurred during blood collections (>90%). The ADR rate of young individuals aged 18-29 years old was the highest (p<0.0001). In addition, a higher ADR rate was observed in first-time blood donors, whole blood donors, and blood donors who donated in the mobile sites (p<0.05).

Conclusion: The occurrence of ADRs is related to the sociodemographic factors of blood donors, including age, donation type, donation history, and donation sites. Shenzhen Blood Centers should pay special attention to the process of blood donation among young blood donors aged 18-29 years old, first-time blood donors, whole-blood donors, and blood donors who donate at mobile sites to further reduce the occurrence of ADRs.

Keywords: adverse donor reactions; blood donors; sociodemographic factors.

Grants and funding

This study was financially supported by National Natural Science Foundation of China (No. 82261138630), Shenzhen Key Discipline Project of Blood Transfusion Medicine (No. SZXK070), Research project of Shenzhen Blood Center (No. SZBC202210).