Spinal cord ischemia revealed by a Brown-Sequard syndrome and caused by a calcified thoracic disc extrusion with spontaneous regression: a case report and review of the literature

J Med Case Rep. 2023 Nov 29;17(1):510. doi: 10.1186/s13256-023-04208-1.

Abstract

Background: Thoracic disc herniation is relatively uncommon, accounting for less than 1% of all spinal herniations. Although most often asymptomatic, they may represent a rare cause of spinal cord ischemia.

Case report: We report the case of a healthy 43-year-old North African male who presented with a Brown-Sequard syndrome revealing a spinal cord ischemia caused by a thoracic disc extrusion. The initial MRI revealed a calcified disc extrusion at the level of T5-T6 without significant spinal cord compression or signal abnormality. A pattern consistent with a medullary ischemia only appeared 48 h later. The patient was treated conservatively with Aspirin and Heparin, which were discontinued later because of a negative cardiovascular work-up. The calcified disc extrusion, which was later recognized as the cause of the ischemia, decreased spontaneously over time and the patient recovered within a few months.

Conclusions: Our case highlights the challenge in diagnosing and managing this uncommon condition. We propose a literature review showing the different therapeutic strategies and their corresponding clinical outcomes.

Keywords: Brown-Sequard syndrome; Case report; Disc herniation; Spinal cord ischemia.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Adult
  • Brown-Sequard Syndrome* / diagnostic imaging
  • Brown-Sequard Syndrome* / etiology
  • Hernia
  • Humans
  • Intervertebral Disc Displacement* / complications
  • Intervertebral Disc Displacement* / diagnostic imaging
  • Ischemia
  • Magnetic Resonance Imaging
  • Male
  • Spinal Cord Ischemia* / complications