Relationship Between Preoperative Inflammation Ratios Derived From Preoperative Blood Cell Count and Postoperative Pulmonary Complications in Patients Undergoing Lobectomy: A Single-Center Observational Study

J Cardiothorac Vasc Anesth. 2024 Feb;38(2):482-489. doi: 10.1053/j.jvca.2023.11.001. Epub 2023 Nov 4.

Abstract

Objective: Evaluation of the association of inflammatory cell ratios, especially neutrophil-to-lymphocyte ratio (NLR), based on preoperative complete blood counts, with postoperative complications in lobectomy surgery.

Design: This was a retrospective monocentric cohort study.

Setting: The study was conducted at Foch University Hospital in Suresnes, France.

Participants: Patients having undergone a scheduled lobectomy from January 2018 to September 2021.

Interventions: There were no interventions.

Measurements and main results: The authors studied 208 consecutive patients. Preoperative NLR, monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, systemic inflammation index, systemic inflammation response index, and aggregate inflammation systemic index were calculated. Median and (IQR) of NLR was 2.67 (1.92-3.69). No statistically significant association was observed between any index and the occurrence of at least one major postoperative complication, which occurred in 37% of the patients. Median postoperative length of stay was 7 (5-10) days. None of the ratios was associated with prolonged length of stay (LOS), defined as a LOS above the 75th percentile.

Conclusions: The results suggested that simple available inflammatory ratios are not useful for the preoperative identification of patients at risk of postoperative major complications in elective lobectomy surgery.

Keywords: blood cell count; length of stay; lobectomy; postoperative complications.

Publication types

  • Observational Study

MeSH terms

  • Blood Cell Count
  • Cohort Studies
  • Humans
  • Inflammation* / diagnosis
  • Inflammation* / epidemiology
  • Inflammation* / etiology
  • Lymphocyte Count
  • Postoperative Complications* / diagnosis
  • Postoperative Complications* / epidemiology
  • Postoperative Complications* / etiology
  • Retrospective Studies