Venetoclax plus hypomethylating agents in newly diagnosed acute myeloid leukemia patients with RUNX1::RUNX1T1: a retrospective propensity score matching study

Miao Wang; Han-Yu Cao; Kai-Wen Tan; Qiao-Cheng Qiu; Yuan-Hong Huang; Shuai-Shuai Ge; Zi-Hao Wang; Jia Chen; Xiao-Wen Tang; De-Pei Wu; Sheng-Li Xue; Zheng Li; Hai-Ping Dai

doi:10.1038/s41408-023-00948-x

Venetoclax plus hypomethylating agents in newly diagnosed acute myeloid leukemia patients with RUNX1::RUNX1T1: a retrospective propensity score matching study

Blood Cancer J. 2023 Nov 27;13(1):173. doi: 10.1038/s41408-023-00948-x.

Authors

Miao Wang^#^{1

2}, Han-Yu Cao^#^{1

2}, Kai-Wen Tan^#^{1

2}, Qiao-Cheng Qiu^{1

2}, Yuan-Hong Huang^{1

2}, Shuai-Shuai Ge^{1

2}, Zi-Hao Wang^{1

2}, Jia Chen^{1

2}, Xiao-Wen Tang^{1

2}, De-Pei Wu^{1

2}, Sheng-Li Xue^{3

4}, Zheng Li^{5

6}, Hai-Ping Dai^{7

8}

Affiliations

¹ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
² Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
³ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China. slxue@suda.edu.cn.
⁴ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China. slxue@suda.edu.cn.
⁵ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China. lzheng@suda.edu.cn.
⁶ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China. lzheng@suda.edu.cn.
⁷ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China. daihaiping8@126.com.
⁸ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China. daihaiping8@126.com.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / adverse effects
Bridged Bicyclo Compounds, Heterocyclic / therapeutic use
Core Binding Factor Alpha 2 Subunit* / genetics
Humans
Leukemia, Myeloid, Acute* / diagnosis
Leukemia, Myeloid, Acute* / drug therapy
Leukemia, Myeloid, Acute* / genetics
Propensity Score
RUNX1 Translocation Partner 1 Protein
Retrospective Studies

Substances

venetoclax
Core Binding Factor Alpha 2 Subunit
Bridged Bicyclo Compounds, Heterocyclic
RUNX1T1 protein, human
RUNX1 Translocation Partner 1 Protein
RUNX1 protein, human

Grants and funding

81970138/National Natural Science Foundation of China (National Science Foundation of China)