Diagnosis and Management of Bullous Disease

Clin Geriatr Med. 2024 Feb;40(1):37-74. doi: 10.1016/j.cger.2023.09.002. Epub 2023 Oct 5.

Abstract

Bullous diseases are a group of dermatoses primarily characterized by the presence of vesicles (0.1-0.9 cm) or bullae (>1 cm). There are various categories of bullous disease: allergic, autoimmune, infectious, mechanical, and metabolic. These diseases affect individuals in all decades of life, but older adults, age 65 and older, are particularly susceptible to bullous diseases of all etiologies. The incidence of these disorders is expected to increase given the advancing age of the general population. In this comprehensive review, we will outline the common bullous diseases affecting older individuals and provide an approach to evaluation and management.

Keywords: Anatomic level; Bullous diseases; Dermatoses; General population.

Publication types

  • Review

MeSH terms

  • Aged
  • Humans
  • Skin Diseases, Vesiculobullous* / diagnosis
  • Skin Diseases, Vesiculobullous* / etiology
  • Skin Diseases, Vesiculobullous* / therapy