Protocol to fabricate wearable stretchable microneedle-based sensors

Rawan Omar; Youbin Zheng; Hossam Haick

doi:10.1016/j.xpro.2023.102751

Protocol to fabricate wearable stretchable microneedle-based sensors

STAR Protoc. 2023 Dec 15;4(4):102751. doi: 10.1016/j.xpro.2023.102751. Epub 2023 Nov 23.

Authors

Rawan Omar¹, Youbin Zheng², Hossam Haick³

Affiliations

¹ Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion-Israel Institute of Technology, Haifa 3200003, Israel. Electronic address: rawan.omar143@gmail.com.
² Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion-Israel Institute of Technology, Haifa 3200003, Israel; Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool L69 3GJ, UK. Electronic address: youbin.zheng@liverpool.ac.uk.
³ Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion-Israel Institute of Technology, Haifa 3200003, Israel. Electronic address: hhossam@technion.ac.il.

Abstract

Creating highly stretchable and robust electrodes while retaining conductivity and stability is challenging. Furthermore, combining these elastic parts with rigid ones brings its own problems due to the discrepancy in firmness between the flexible patches and rigid constructions. Here, we present a protocol to create a stable, conductive, and flexible microneedle sensor patch. We describe steps for using polystyrene-block-polyisoprene-block-polystyrene with silver nanowires, besides fabricating rigid microneedles and combining them together using a thickness-gradient strategy. For complete details on the use and execution of this protocol, please refer to Zheng et al. (2022).¹.

Keywords: Antibody; Biotechnology and bioengineering; Chemistry; Health Sciences; Material sciences; Molecular/Chemical Probes.

MeSH terms

Drug Delivery Systems
Nanowires*
Silver
Wearable Electronic Devices*

Substances

Silver