Cross-language generalization of language treatment in multilingual people with post-stroke aphasia: A meta-analysis

Brain Lang. 2023 Nov:246:105326. doi: 10.1016/j.bandl.2023.105326. Epub 2023 Oct 31.

Abstract

Studies on the efficacy of language treatment for multilingual people with post-stroke aphasia and its generalization to untreated languages have produced mixed results. We conducted a systematic review and a meta-analysis to examine within- and cross-language treatment effects and the variables that affect them. We searched PubMed, PsycINFO, CINAHL, and Google Scholar (February 2020; January 2023), identifying 40 studies reporting on 1573 effect sizes from 85 individuals. We synthesized effect sizes for treatment outcomes using a multi-level model to correct for multiple observations from the same individuals. The results showed significant treatment effects, with robust within-language treatment effects and weaker cross-language treatment effects. Age of language acquisition of the treatment language predicted within-language and cross-language effects. Our results suggest that treating multilingual people with aphasia in one language may generalize to their other languages, especially following treatment in an early-acquired language and a later-learned language that became the language of immersion.

Keywords: Aphasia; Bilingual; Cross-language generalization; Intervention; Meta-analysis; Multilingual; Treatment.

Publication types

  • Systematic Review
  • Meta-Analysis
  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aphasia* / etiology
  • Aphasia* / therapy
  • Humans
  • Language
  • Language Development
  • Multilingualism*
  • Treatment Outcome