Chemical Peels in Treatment of Melasma

Dermatol Clin. 2024 Jan;42(1):21-32. doi: 10.1016/j.det.2023.06.003. Epub 2023 Jul 18.

Abstract

Superficial chemical peels are one of the most popular skin resurfacing procedures in a dermatologists' clinic today due to quick application process, fast recovery, good patient acceptance, and excellent cosmetic results. The role of various peeling agents like glycolic acid, salicylic acid, trichloroacetic acid, Jessner's solution, retinoic acid, and lactic acid in the management of melasma has been established as that of an additional or maintenance therapy. This article details the current evidence and recommendations for the use of chemical peels in the treatment of melasma, a chronic and recurrent hyperpigmentary disorder.

Keywords: Chemical peels; Glycolic acid; Jessner's solution; Lactic acid; Melasma; Salicylic acid; Tretinoin peel; Trichloroacetic acid.

Publication types

  • Review

MeSH terms

  • Chemexfoliation* / methods
  • Drug Combinations
  • Humans
  • Keratolytic Agents / therapeutic use
  • Melanosis* / therapy
  • Salicylic Acid / therapeutic use
  • Trichloroacetic Acid / therapeutic use

Substances

  • Salicylic Acid
  • Keratolytic Agents
  • Trichloroacetic Acid
  • Drug Combinations