Parkinson's Disease: Advances in Treatment and the Syntheses of Various Classes of Pharmaceutical Drug Substances

David R Hill; Alexander D Huters; Timothy B Towne; Rajarathnam E Reddy; Jace L Fogle; Eric A Voight; Philip R Kym

doi:10.1021/acs.chemrev.3c00479

Parkinson's Disease: Advances in Treatment and the Syntheses of Various Classes of Pharmaceutical Drug Substances

Chem Rev. 2023 Dec 13;123(23):13693-13712. doi: 10.1021/acs.chemrev.3c00479. Epub 2023 Nov 17.

Authors

David R Hill, Alexander D Huters, Timothy B Towne, Rajarathnam E Reddy, Jace L Fogle, Eric A Voight, Philip R Kym

PMID: 37975808
DOI: 10.1021/acs.chemrev.3c00479

Abstract

An overview of Parkinson's disease (PD) prevalence, diagnosis, and currently available treatment options is provided. A comprehensive list of different classes of marketed pharmaceutical drug products and the syntheses of various drug substances are summarized based on published literature.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Antiparkinson Agents* / classification
Humans
Parkinson Disease* / diagnosis
Parkinson Disease* / drug therapy
Parkinson Disease* / epidemiology
Pharmaceutical Preparations
Prevalence

Substances

Pharmaceutical Preparations
Antiparkinson Agents