The role of laboratory medicine in a value-based healthcare system: the example of heart failure patient management in the Italian context

Eur Rev Med Pharmacol Sci. 2023 Nov;27(21):10763-10772. doi: 10.26355/eurrev_202311_34356.

Abstract

Objective: As of today, healthcare systems worldwide face severe challenges that undermine their sustainability. The value-based healthcare (VBHC) approach has been proposed as a strategic and methodological framework to ensure the delivery of the best patient outcomes with economic efficiency. Through the illustrative example of B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) for heart failure (HF) patient management in the context of the Italian National Healthcare system, this article explores the role that in vitro diagnostics (IVDs) can play in enabling value-based care models.

Subjects and methods: 14 healthcare professionals representing the relevant professional figures involved in HF patient management met to revise the current HF patient journey and design a new care pathway that, leveraging on BNP/NT-proBNP, reflects the VBHC principles.

Results: The literature recognizes the dosage of BNP/NT-proBNP as the gold stan-dard for diagnosing HF. However, as of today, these IVDs are not employed at their full potential regarding HF patient management. A new patient journey is proposed so that patients are diagnosed early and properly monitored in the aftermath of hospitalization, improving outcomes at contained costs.

Conclusions: As testified by the example of HF patient management in Italy, laboratory medicine can represent a lever for adopting value-based care models. Still, large-scale adoption of VBHC will call for structural reforms that revise how healthcare delivery is organized, measured, and reimbursed.

MeSH terms

  • Biomarkers
  • Heart Failure* / diagnosis
  • Heart Failure* / therapy
  • Hospitalization
  • Humans
  • Natriuretic Peptide, Brain / metabolism
  • Patients
  • Peptide Fragments / metabolism
  • Prognosis
  • Value-Based Health Care*

Substances

  • Natriuretic Peptide, Brain
  • Peptide Fragments
  • Biomarkers