Endoscopic Ultrasound-Guided Antitumor Therapy

Abstract

Endoscopic ultrasound (EUS) has been used for various interventions to manage intra-abdominal lesions. EUS-guided antitumor therapy via delivery of chemotherapeutic agents, energy, and radioactive seeds has advantages of less invasiveness than surgical approaches, and the anatomic proximity allows easy and accurate access to the pancreas. The feasibility of EUS-guided antitumor therapy has been reported both in pancreatic solid and cystic neoplasms, with promising preliminary results. Randomized controlled trials are mandatory to further confirm its role.

Keywords: Ablation; Endoscopic ultrasound; Fine-needle injection; Oncolytic viral therapy; Radiofrequency ablation.