Performance evaluation of Espline HTLV-I/II, a newly developed rapid immunochromatographic antibody test for different diagnostic situations

Microbiol Spectr. 2023 Dec 12;11(6):e0207823. doi: 10.1128/spectrum.02078-23. Epub 2023 Nov 15.

Abstract

The World Health Organization estimated that 5-10 million people are infected with human T-cell leukemia virus type 1 (HTLV-1). This number is likely to be underestimated because reliable endemic data are available for only approximately 1.5 billion people worldwide. The point-of-care test is a powerful tool for the easy and quick detection of infections without the requirement for expensive instruments and laboratory equipment. Espline HTLV-I/II, a newly developed rapid immunochromatographic antibody test that was evaluated in this study, might significantly advance our understanding of the global epidemiology of HTLV-1 infection.

Keywords: HTLV-1; immunochromatographic antibody test; point-of-care test; sensitivity; specificity.

MeSH terms

  • HTLV-I Infections* / diagnosis
  • HTLV-I Infections* / epidemiology
  • Human T-lymphotropic virus 1*
  • Humans