A Potential Partnership between Genetics and the Oral Microbiome in Children Displaying Periodic Fever/Aphthosis/Pharyngitis/Adenitis Syndrome

Int J Mol Sci. 2023 Oct 24;24(21):15505. doi: 10.3390/ijms242115505.

Donato Rigante^{1

2}, Lea Calò^{2

3}, Alessandro Ciavarro⁴, Jacopo Galli^{2

3}

¹ Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy.
² School of Medicine, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
³ Complex Unit of Otolaryngology, Department of Aging, Neurological, Orthopedic and Head and Neck Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy.
⁴ Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Via Cracovia 50, 00133 Rome, Italy.

Abstract

Periodic fever/aphthosis/pharyngitis/adenitis (PFAPA) syndrome was initially described in a small cohort of American children [...].