Studying Long QT Syndrome Caused by NAA10 Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells

Circulation. 2023 Nov 14;148(20):1598-1601. doi: 10.1161/CIRCULATIONAHA.122.061864. Epub 2023 Nov 13.
No abstract available

Keywords: Cav1.2 calcium channel; NAA10; iPSC; long QT; rare disease.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Induced Pluripotent Stem Cells*
  • Long QT Syndrome* / diagnosis
  • Long QT Syndrome* / genetics
  • Mutation
  • Myocytes, Cardiac
  • N-Terminal Acetyltransferase A / genetics
  • N-Terminal Acetyltransferase E / genetics
  • Phenotype

Substances

  • NAA10 protein, human
  • N-Terminal Acetyltransferase A
  • N-Terminal Acetyltransferase E