Recurrence of Rathke's Cleft Cyst Following Surgery and Histopathological Considerations for Recurrence: A Case Presentation

Dongwook Lee; Jang Hun Kim; Dong-Hyuk Park; Shin-Hyuk Kang; Kyung-Jae Park

doi:10.14791/btrt.2023.0025

Recurrence of Rathke's Cleft Cyst Following Surgery and Histopathological Considerations for Recurrence: A Case Presentation

Brain Tumor Res Treat. 2023 Oct;11(4):266-270. doi: 10.14791/btrt.2023.0025.

Authors

Dongwook Lee¹, Jang Hun Kim¹, Dong-Hyuk Park¹, Shin-Hyuk Kang¹, Kyung-Jae Park²

Affiliations

¹ Department of Neurosurgery, Anam Hospital, Korea University Medical Center, Korea University College of Medicine, Seoul, Korea.
² Department of Neurosurgery, Anam Hospital, Korea University Medical Center, Korea University College of Medicine, Seoul, Korea. kyungjae99@hanmail.net.

Abstract

Recurrence of Rathke's cleft cysts (RCC) following surgery is not uncommon. We present a 33-year-old male patient with chronic headache and visual disturbances whose MRI showed mostly cystic, suprasellar mass with peripheral enhancement. Endoscopic extended transsphenoidal approach and tumor resection was performed and RCC was pathologically confirmed postoperatively. Early recurrence was first suspected at 3 months following surgery, and his serial MRIs showed a recurred mass without associated clinical symptoms. Upon further histopathological study, extensive squamous metaplasia and high Ki-67 were seen. Also, in this study, we discuss important factors associated with cyst recurrence following surgery.

Keywords: Craniopharyngioma; Ki-67; Rathke's cleft cysts; Squamous metaplasia; Suprasellar cysts.

Publication types

Case Reports