Impacts of shelter management on canine rabies immune status

Navapon Techakriengkrai; Sirikittiya Aryuman; Kraijaras Vanlarat; Chanachan Karnchanapraphas; Chananchida Kimsang; Nichapat Rojjananavin; Teerawut Nedumpun; Sanipa Suradhat

doi:10.1016/j.vaccine.2023.11.018

Impacts of shelter management on canine rabies immune status

Vaccine. 2023 Nov 30;41(49):7313-7316. doi: 10.1016/j.vaccine.2023.11.018. Epub 2023 Nov 10.

Authors

Navapon Techakriengkrai¹, Sirikittiya Aryuman², Kraijaras Vanlarat², Chanachan Karnchanapraphas², Chananchida Kimsang², Nichapat Rojjananavin³, Teerawut Nedumpun³, Sanipa Suradhat⁴

Affiliations

¹ Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand; Center of Excellence in Diagnosis and Monitoring of Animal Pathogens, Chulalongkorn University, Bangkok, 10330, Thailand. Electronic address: navapon.t@chula.ac.th.
² Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
³ Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
⁴ Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: sanipa.s@chula.ac.th.

PMID: 37951794
DOI: 10.1016/j.vaccine.2023.11.018

Abstract

Rabies vaccination is mandatory in dogs in Thailand. In this study, shelter management quality and rabies immune status were evaluated by questionnaire and rabies virus neutralising antibody (RVNA) measurement. The questionnaire was designed to assess all relevant factors of shelter management, which could impact the rabies vaccine antibody response. Thirteen participating shelters were classified into 4 groups, namely group A (best), B (good), C (fair), and D (require improvement). Sera were collected from randomly selected dogs (n = 113) within 4 weeks after rabies re-vaccination from a representative shelter of group B, C and D. Sample from group A was not included in the study due to time limitation. Both the number of dogs with acceptable response (RVNA ≥ 0.5 IU/ml) and the RVNA titres were significantly higher in group B than group C and D. Our results indicate that the quality of shelter management could affect rabies immune status.

Keywords: Immune status; Neutralising antibodies; Rabies vaccine; Shelter dogs; Shelter management.

MeSH terms

Animals
Antibodies, Blocking
Antibodies, Viral
Dogs
Rabies Vaccines*
Rabies virus*
Rabies* / prevention & control
Rabies* / veterinary
Vaccination / veterinary

Substances

Rabies Vaccines
Antibodies, Viral
Antibodies, Blocking