A Brief Review of Bone Cell Function and Importance

Veronika Šromová; Dinara Sobola; Pavel Kaspar

doi:10.3390/cells12212576

A Brief Review of Bone Cell Function and Importance

Cells. 2023 Nov 5;12(21):2576. doi: 10.3390/cells12212576.

Authors

Veronika Šromová^{1

2}, Dinara Sobola³, Pavel Kaspar²

Affiliations

¹ Department of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, 601 90 Brno, Czech Republic.
² Department of Physics, Faculty of Electrical Engineering and Communication, Brno University of Technology, 601 90 Brno, Czech Republic.
³ Academy of Sciences of the Czech Republic, Institute of Physics of Materials, Žižkova 22, 616 62 Brno, Czech Republic.

Abstract

This review focuses on understanding the macroscopic and microscopic characteristics of bone tissue and reviews current knowledge of its physiology. It explores how these features intricately collaborate to maintain the balance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption, which plays a pivotal role in shaping not only our physical framework but also overall health. In this work, a comprehensive exploration of microscopic and macroscopic features of bone tissue is presented.

Keywords: bone cells; microscopic and macroscopic intricacies; physiology of bone tissue.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Bone Resorption*
Bone and Bones
Cell Differentiation / physiology
Humans
Osteoblasts / physiology
Osteoclasts* / physiology

Grants and funding

The research described in the paper was supported by the Internal Grant Agency of the Brno University of Technology, grant No. FEKT-S-20-6352. DS acknowledges projects: CSF no. 20-11321S and AZV no. NU20-08-00149.