Advanced Sinonasal Malignant Melanoma; A Case Report

Iran J Pathol. 2023 Summer;18(3):376-379. doi: 10.30699/IJP.2023.553175.2987. Epub 2023 Jul 16.

Abstract

Malignant melanoma of the sinonasal area is a rare tumor that arises from melanocytes in the nasal mucosa and is more aggressive than the cutaneous type with a poor prognosis. We report a 60-year-old female with the initial chief complaint of nasal cavity fullness, continuous epistaxis, and nasal bone deformity in the past two months. In a primary examination, a black mass was found, and in an excisional biopsy, the pathologist reported sinonasal malignant melanoma, which was confirmed after IHC staining. In spindle cell tumors of the head and neck area, we should be aware of mucosal malignant melanoma as a differential diagnosis.

Keywords: Epistaxis; Malignant melanoma; Mucosal melanoma; Sinonasal.

Publication types

  • Case Reports