CNS therapeutics: Immune cells break the barriers

Sci Transl Med. 2023 Nov 8;15(721):eadh1150. doi: 10.1126/scitranslmed.adh1150. Epub 2023 Nov 8.

Abstract

Peripheral immune cells can be seen as attractive vectors and drug carriers for central nervous system therapeutics because these cells have unique properties that allow them to migrate across the blood-brain barrier, enabling drug delivery to brain regions that are inaccessible to free drugs.

Publication types

  • Review

MeSH terms

  • Blood-Brain Barrier
  • Brain
  • Central Nervous System Diseases* / drug therapy
  • Central Nervous System*
  • Drug Carriers
  • Drug Delivery Systems
  • Humans

Substances

  • Drug Carriers