Proton versus photon therapy for esophageal cancer - A trimodality strategy (PROTECT) NCT050555648: A multicenter international randomized phase III study of neoadjuvant proton versus photon chemoradiotherapy in locally advanced esophageal cancer

Affiliations

• ¹ Danish Center for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Aarhus, Denmark.
• ² University Hospitals Leuven, Department of Radiation Oncology, Belgium; KU Leuven- University of Leuven, Department of Oncology, Laboratory of Experimental Radiotherapy, Leuven, Belgium.
• ³ Department of Oncology and Medical Physics, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Aarhus, Denmark.
• ⁴ University of Leeds, Leeds, UK.
• ⁵ University Hospitals Leuven, Department of Thoracic Surgery, Belgium.
• ⁶ Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
• ⁷ Danish Center for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
• ⁸ Department of Medical Physics and Biomedical Engineering, University College London, London, UK.
• ⁹ Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany; OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, and Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology - OncoRay Helmholtz-Zentrum Dresden-Rossendorf, Germany.
• ¹⁰ KU Leuven- University of Leuven, Department of Oncology, Laboratory of Experimental Radiotherapy, Leuven, Belgium.
• ¹¹ Department of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, the Netherlands.
• ¹² Research Dept. of Primary Care and Population Health, University College London, London, UK.
• ¹³ Center for Proton Therapy, Paul Scherrer Institut, Villigen, Switzerland; Radiation Oncology Department, University Hospital Zurich, Zurich, Switzerland.
• ¹⁴ Department of Oncology and Medical Physics, Aarhus University Hospital, Aarhus, Denmark.
• ¹⁵ NHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia.
• ¹⁶ Dept. Surgery and Transplantation, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
• ¹⁷ Department of General Surgery, Oxford University Hospitals, Oxford, UK; Nuffield Department of Surgery, University of Oxford, Oxford, UK.
• ¹⁸ The Christie, Manchester, United Kingdom.
• ¹⁹ Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands.
• ²⁰ Proton Therapy Center, Azienda Provinciale per i Servizi Sanitari, Trento, Italy.
• ²¹ National Center for Oncological Hadrontherapy (CNAO), Radiation Oncology Clinical Department, Pavia, Italy.
• ²² Centre Antoine Lacassagne, Nice, France.
• ²³ Centre Léon Bérard, 28 rue Laennec, Lyon 69373 Cedex 08, France.
• ²⁴ PSL Research University, RadiationOncology Department, Institut Curie, Paris/Orsay, France.
• ²⁵ Department of Radiation Oncology, UniversityMedicalCentreGroningen, Groningen, The Netherlands.
• ²⁶ University of Auckland, Waipara Taumata Rau, Auckland, New Zealand.
• ²⁷ Erasmus School of Health Policy and Management, Erasmus University Rotterdam, P.O. Box 1738, Rotterdam, 3000 DR, The Netherlands; Erasmus Centre for Health Economics Rotterdam, Erasmus University, Rotterdam, The Netherlands.
• ²⁸ Department of Oncology and Medical physics, Aarhus University Hospital, Aarhus, Denmark.
• ²⁹ Maastro Proton Therapy, Department of Radiation Oncology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
• ³⁰ Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, and Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology - OncoRay Helmholtz-Zentrum Dresden-Rossendorf, Germany.