Transition-Metal-Catalyzed Directed C-H Functionalization in/on Water

Tariq A Shah; Tanumay Sarkar; Subhradeep Kar; Prabhat Kumar Maharana; Kangkan Talukdar; Tharmalingam Punniyamurthy

doi:10.1002/asia.202300815

Transition-Metal-Catalyzed Directed C-H Functionalization in/on Water

Chem Asian J. 2024 Jan 2;19(1):e202300815. doi: 10.1002/asia.202300815. Epub 2023 Nov 6.

Authors

Tariq A Shah¹, Tanumay Sarkar², Subhradeep Kar², Prabhat Kumar Maharana², Kangkan Talukdar², Tharmalingam Punniyamurthy²

Affiliations

¹ Department of Chemistry and Advanced Material Chemistry Center (AMCC), Khalifa University, PO Box, 127788, Abu Dhabi, U.A.E.
² Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, 781039, India.

PMID: 37932013
DOI: 10.1002/asia.202300815

Abstract

Directing group assisted C-H bond functionalization using transition-metal-catalysis has emerged as a reliable synthetic tool for the construction of regioselective carbon-carbon/heteroatom bonds. Off late, "in/on water directed transition-metal-catalysis", though still underdeveloped, has appeared as one of the prominent themes in sustainable organic chemistry. This article covers the advancements, mechanistic insights and application of the sustainable directed C-H bond functionalization of (hetero)arenes in/on water in the presence of transition-metal-catalysis.

Keywords: Directing group; Site-selective C−H Functionalization; reaction in/on water; transition-metal-catalysis.

Publication types

Review

Grants and funding

PDF/2017/2653/science and engineering research board (SERB)