Disseminated juvenile xanthogranulomas with underlying neurotrophic tyrosine receptor kinase fusion and response to larotrectinib

Br J Dermatol. 2024 Jan 23;190(2):283-284. doi: 10.1093/bjd/ljad427.

Authors

Eun Jae Kim¹, Diana Bartenstein Reusch², Hannah Anthony³, Birgitta Schmidt^{1

4}, Kristen Corey^{1

2}, Barbara Degar^{1

3}, Jennifer T Huang^{1

2}

Affiliations

¹ Harvard Medical School.
² Dermatology Section, Division of Immunology, Boston Children's Hospital.
³ Department of Pediatric Oncology, Dana Farber Cancer Institute.
⁴ Department of Pathology, Boston Children's Hospital, Boston, MA, USA.

PMID: 37930319
DOI: 10.1093/bjd/ljad427

No abstract available

MeSH terms

Humans
Neoplasms*
Protein Kinase Inhibitors
Pyrazoles*
Pyrimidines*
Receptor Protein-Tyrosine Kinases
Receptors, Amino Acid*
Xanthogranuloma, Juvenile*

Substances

larotrectinib
tyrosine receptor
Receptor Protein-Tyrosine Kinases
Protein Kinase Inhibitors
Pyrazoles
Pyrimidines
Receptors, Amino Acid