DNA methylation in poultry: a review

Xing Ju; Zhijun Wang; Danfeng Cai; Semiu Folaniyi Bello; Qinghua Nie

doi:10.1186/s40104-023-00939-9

DNA methylation in poultry: a review

J Anim Sci Biotechnol. 2023 Nov 5;14(1):138. doi: 10.1186/s40104-023-00939-9.

Authors

Xing Ju^{1

2}, Zhijun Wang³, Danfeng Cai^{1

2}, Semiu Folaniyi Bello^{1

2}, Qinghua Nie^{4

5}

Affiliations

¹ State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Lingnan Guangdong Laboratory of Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, 510642, China.
² Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, Guangdong, 510642, China.
³ College of Animal Science and Technology, Zhejiang Agriculture and Forestry University, 666 Wusu Road, Lin'an, 311300, China.
⁴ State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Lingnan Guangdong Laboratory of Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, 510642, China. nqinghua@scau.edu.cn.
⁵ Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, Guangdong, 510642, China. nqinghua@scau.edu.cn.

Abstract

As an important epigenetic modification, DNA methylation is involved in many biological processes such as animal cell differentiation, embryonic development, genomic imprinting and sex chromosome inactivation. As DNA methylation sequencing becomes more sophisticated, it becomes possible to use it to solve more zoological problems. This paper reviews the characteristics of DNA methylation, with emphasis on the research and application of DNA methylation in poultry.

Keywords: CpG islands; DNA methylation; Differentially methylated genes; Differentially methylated regions; Poultry.

Publication types

Review

Abstract

Publication types

Grants and funding