Higher MDMX expression was associated with hypomethylating agent resistance and inferior survival in MDS patients, inferring it a potential therapeutic target

Leukemia. 2023 Dec;37(12):2507-2511. doi: 10.1038/s41375-023-02044-2. Epub 2023 Nov 2.

Yu-Hung Wang^{1

2}, Chien-Chin Lin^{3

4}, Kristian Gurashi², Bettina Wingelhofer⁵, Fabio M R Amaral⁵, Chi-Yuan Yao^{1

6}, Hsin Ting Hsieh⁷, Ming Chih Liu⁷, Hsin-An Hou¹, Wen-Chien Chou^{1

6}, Kiran Batta², Daniel H Wiseman², Hwei-Fang Tien^{8

9}

¹ Division of Hematology, National Taiwan University Hospital, Taipei, Taiwan.
² Epigenetics Haematopoiesis Laboratory, Division of Cancer Sciences, The University of Manchester, Manchester, UK.
³ Division of Hematology, National Taiwan University Hospital, Taipei, Taiwan. jake9665@gmail.com.
⁴ Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan. jake9665@gmail.com.
⁵ Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, Manchester, UK.
⁶ Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
⁷ Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan.
⁸ Division of Hematology, National Taiwan University Hospital, Taipei, Taiwan. hftien@ntu.edu.tw.
⁹ Department of Internal Medicine, Fra-Eastern Memorial Hospital, New Taipei City, Taiwan. hftien@ntu.edu.tw.

No abstract available

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