Objective: To study the effectiveness and safety of joint replacement in the clinical treatment of elderly patients with knee degenerative osteoarthritis. To compare the results of arthroplasty with arthroscopic debridement and to investigate the overall effect of arthroplasty on various parameters.
Methods: We included patients whose diagnostic criteria for mid-knee osteoarthritis involved relevant content, and excluded patients with other diseases such as the immune system. The medical records of 90 patients (senile degenerative knee osteoarthritis, 2021.1-2022.12) were selected for retrospective analysis, and patients were grouped according to the surgical treatment plan, and those treated with arthroscopic debridement surgery were included in the control group (a total of 45 cases), those treated with joint replacement were included in the observation group (45 cases in total). The changes in the levels of kinematic parameters, osteoarthritis indicators, quadriceps strength, inflammation indicators, and knee joint function indicators were compared between the groups, and the daily living abilities of the two groups were compared.
Results: The active flexion angle of the observation group was greater than that of the control group, and the varus inclination was smaller than that of the control group, with P < .05; the joint function scores, pain scores, and stiffness scores of the observation group were all lower than those of the control group, with P < .05; the muscle strength of the voluntary movement of the bilateral quadriceps muscle and the maximum muscle strength under isometric contraction was higher than those of the control group, with P < .05; the measured values of interleukin-6, C-reactive protein, and white blood cell count (IL-6, CRP, WBC) in the observation group were lower than those of the control group, with P < .05; the scores of knee joint function and daily living ability in the observation group were higher than those in the control group, with P < .05.
Conclusion: The curative effects of joint replacement in the treatment of senile knee degenerative osteoarthritis are significant, which can promote the improvement of early postoperative kinematic parameters and the recovery of joint function and reduce the inflammatory response. It also promotes the recovery of knee joint function, improves knee joint function, improves patient prognosis, and also improves the daily living abilities of elderly patients with knee joint degenerative osteoarthritis.