Non-replicating vaccinia virus NTV as an effective next-generation smallpox and monkeypox vaccine: evidence from mouse and rhesus monkey models

Qiaohong Chu; Baoying Huang; Mengzhe Li; Xueting Cheng; Shuting Huo; Jiao Ren; Yao Deng; Wenjie Tan

doi:10.1080/22221751.2023.2278900

Non-replicating vaccinia virus NTV as an effective next-generation smallpox and monkeypox vaccine: evidence from mouse and rhesus monkey models

Emerg Microbes Infect. 2023 Dec;12(2):2278900. doi: 10.1080/22221751.2023.2278900. Epub 2023 Dec 6.

Authors

Qiaohong Chu¹, Baoying Huang¹, Mengzhe Li², Xueting Cheng¹, Shuting Huo¹, Jiao Ren¹, Yao Deng¹, Wenjie Tan^{1

2}

Affiliations

¹ NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.
² School of Public Health, Xinxiang Medical University, Xinxiang, People's Republic of China.

No abstract available

MeSH terms

Animals
Macaca mulatta
Mice
Mpox (monkeypox)* / prevention & control
Smallpox Vaccine*
Smallpox* / prevention & control
Vaccinia virus / genetics

Substances

Smallpox Vaccine

Grants and funding

This research was supported by the National Key Research and Development Program of China (2022YFC2304100, 2022YFC2303401, 2021YFA1201003) and National Natural Science Foundation of China (82041041).