Electrophoretically deposited titanium and its alloys in biomedical engineering: Recent progress and remaining challenges

J Biomed Mater Res B Appl Biomater. 2024 Jan;112(1):e35342. doi: 10.1002/jbm.b.35342. Epub 2023 Oct 31.

Abstract

Over the past decade, titanium implants have gained popularity as the number of performed implantation operations has significantly increased. There are a number of methods for modifying the surface of biomaterials, which are aimed at extending the life of titanium implants. The developments in this field in recent years have required a comprehensive discussion of all the properties of electrophoretically deposited coatings on titanium and its alloys, taking into account their bioactivity. The development that took place in this field in recent years required a comprehensive discussion of all the properties of coatings electrophoretically deposited on titanium and its alloys, with particular emphasis on their bioactivity. Herein, we attempt to assess the influence of the electrophoretic deposition (EPD) process parameters on these coatings' biological and mechanical properties. Particular attention has been addressed to the in-vitro and in-vivo studies conducted hitherto. We have seen an increased interest in using titanium alloys without the addition of toxic compounds and gaps in the EPD field such as the uncommon endeavors to develop a "Design of experiments" approach as well as the lack of assessment of the surface free energy and detailed topography of electrophoretically deposited coatings. The exact correlation of coating properties with EPD process parameters still seems explicitly not understood, necessitating more future investigations. Ipso facto, the exact mechanism of particle agglomeration and Hamaker's law need to be fathomable.

Keywords: biomaterials; biomedical application; coatings; electrophoretic deposition; implants; titanium alloys.

Publication types

  • Review

MeSH terms

  • Alloys*
  • Biomedical Engineering
  • Coated Materials, Biocompatible
  • Prostheses and Implants
  • Surface Properties
  • Titanium*

Substances

  • Alloys
  • Titanium
  • Coated Materials, Biocompatible