Targeted next-generation sequencing technology showed great potential in identifying spinal tuberculosis and predicting the drug resistance

Guang Zhang; Hongqi Zhang; Ye Zhang; Xiaojiang Hu; Mingxing Tang; Qile Gao

doi:10.1016/j.jinf.2023.10.018

Targeted next-generation sequencing technology showed great potential in identifying spinal tuberculosis and predicting the drug resistance

J Infect. 2023 Dec;87(6):e110-e112. doi: 10.1016/j.jinf.2023.10.018. Epub 2023 Oct 26.

Authors

Guang Zhang¹, Hongqi Zhang², Ye Zhang³, Xiaojiang Hu⁴, Mingxing Tang⁵, Qile Gao⁶

Affiliations

¹ Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China. Electronic address: diaizhang14185@163.com.
² Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China. Electronic address: zhq9996@163.com.
³ Department of Scientific Affairs, Hugobiotech Co., Ltd., No.1, East Disheng Road, Beijing 100176, China. Electronic address: zhangye@hugobiotech.com.
⁴ Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China. Electronic address: huxiaojiang2021@163.com.
⁵ Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China. Electronic address: 42095581@qq.com.
⁶ Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, China. Electronic address: gaoql@csu.edu.cn.

PMID: 37898411
DOI: 10.1016/j.jinf.2023.10.018

No abstract available

Publication types

Letter

MeSH terms

Antitubercular Agents / pharmacology
Antitubercular Agents / therapeutic use
Drug Resistance
High-Throughput Nucleotide Sequencing
Humans
Mycobacterium tuberculosis* / genetics
Technology
Tuberculosis, Multidrug-Resistant* / diagnosis
Tuberculosis, Multidrug-Resistant* / drug therapy
Tuberculosis, Spinal* / diagnosis

Substances

Antitubercular Agents