Global Elimination of HCV-Why Is Poland Still So Far from the Goal?

Viruses. 2023 Oct 9;15(10):2067. doi: 10.3390/v15102067.

Abstract

Introduction: Eradication of HCV in the global population remains one of the greatest challenges faced by the WHO. An insufficient level of knowledge and the lack of a national screening test strategy are obstacles to HCV eradication.

Aim: This work aimed to summarize surveys assessing risk factors and awareness of the respondents regarding the prevention and course of HCV infection. The summary also includes the most important European and global attempts at eliminating HCV.

Materials and methods: A cross-sectional, population-based study was conducted in the Mazowieckie district in Poland using anonymous surveys and conducted on people who willingly reported for a test.

Results: In the study cohort of n = 7397 adults, there were 5412 women (73.16%). The analysis of the quota sample (n = 1303) reflected the actual proportions in the population of the Mazowieckie Voivodeship.

Conclusions: Insufficient knowledge about HCV decreases the probability of higher detection of infections, fast diagnostics, and treatment. According to the WHO model, assuming a 90% detection rate and treatment of 80% of infected by 2030, and taking into account 120-150 thousand infected persons in Poland, the number of detections of HCV should be increased 4-5 times and all diagnosed persons should be offered antiviral treatment.

Keywords: chronic hepatitis C; direct-acting antivirals; elimination of hepatitis C virus infection; national action plan for eliminating hepatitis C.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antiviral Agents / therapeutic use
  • Cross-Sectional Studies
  • Female
  • Goals*
  • Hepacivirus
  • Hepatitis C* / diagnosis
  • Hepatitis C* / epidemiology
  • Hepatitis C* / prevention & control
  • Humans
  • Poland / epidemiology

Substances

  • Antiviral Agents

Grants and funding

This research was financed with funds from the Mazowieckie Voivodeship local government.