Spontaneous regression of choroidal metastasis from renal cell carcinoma

Sean M Rodriguez; H Culver Boldt; Hannah R Sullivan; John M Rieth; Yousef Zakharia; Elaine M Binkley

doi:10.1016/j.ajoc.2023.101945

Spontaneous regression of choroidal metastasis from renal cell carcinoma

Am J Ophthalmol Case Rep. 2023 Oct 20:32:101945. doi: 10.1016/j.ajoc.2023.101945. eCollection 2023 Dec.

Authors

Sean M Rodriguez¹, H Culver Boldt^{1

2}, Hannah R Sullivan³, John M Rieth³, Yousef Zakharia³, Elaine M Binkley^{1

2}

Affiliations

¹ Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA, 52242, USA.
² Institute for Vision Research, 451 Newton Road, 200 Medicine Administration Building, Iowa City, IA, 52242, USA.
³ Department of Internal Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA, 52242, USA.

Abstract

Purpose: To report a case of an elderly man who presented with a choroidal metastasis from renal cell carcinoma that spontaneously regressed prior to any local or systemic treatment.

Observations: An 82-year-old man without a history of metastatic cancer was referred to the ocular oncology service for evaluation of a newly noted amelanotic choroidal lesion. Examination and imaging findings were concerning for choroidal metastasis. Systemic workup revealed previously undiagnosed widely metastatic renal cell carcinoma. The lesion spontaneously regressed prior to the initiation of any treatment for his tumor.

Conclusions and importance: This is a unique case of choroidal metastases from renal cell carcinoma that spontaneously regressed prior to medical or surgical treatment of the primary tumor.

Keywords: Choroidal metastasis; Renal cell carcinoma; Uveal metastasis.

Publication types

Case Reports