For liquids used in biological applications, a smaller diffusion coefficient results in a longer mixing time. We discuss, in this endeavor, the promising potential of the AC electrothermal (ACET) effect toward modulating enhanced mixing of electrolytic liquids with higher convective strength in a novel wavy micromixer. To this end, we develop a modeling framework and numerically solve the pertinent transport equations in a three-dimensional (3D) configuration numerically. By benchmarking the developed modeling framework with the experimental results available in this paradigm, we aptly demonstrate the maximum temperature rise, flow topology, species concentration field, and mixing efficiency in the proposed configuration for a set of parameters pertinent to this analysis. We find that the maximum temperature increase in the wavy micromixer, owing to the electrothermal effect, is less than 10 K even for the higher strength of the applied voltage, implying nondegradation of biological substances within the liquid sample. We report that the formation of significant lateral flow closer to the electrodes leads to a highly three-dimensional ACET flow field, which has a significant impact on the mixing efficiency for the range of diffusive Peclet numbers considered. We also report that the wave amplitude of the mixer, when intervening with the diffusive Peclet number, strongly impacts the mixing efficiency. As witnessed in this endeavor, for the smaller diffusive Peclet number, the mixing efficiency increases with amplitude, while the effect becomes the opposite for the higher Peclet number. The results of this study seem to provide an adequate basis for the design of a novel micromixer intended for enhanced solute mixing in realistic microfluidic applications.