Recent Updates on the Antimicrobial Compounds from Marine-Derived Penicillium fungi

Chem Biodivers. 2023 Dec;20(12):e202301278. doi: 10.1002/cbdv.202301278. Epub 2023 Nov 14.

Abstract

In this review, 72 compounds isolated from marine-derived Penicillium fungi and their antimicrobial activities are reviewed from 2020 to 2023. According to their structures, these compounds can be divided into terpenoids, polyketides, alkaloids and other structural compounds, among which terpenoids and polyketides are relatively large in number. Some compounds have powerful inhibitory effects against different pathogenic bacteria and fungi. This review aims to provide more useful information and enlightenment for further efficient utilization of Penicillium spp. and their secondary metabolites.

Keywords: Antimicrobial activity; Fungi; Marine environment; Natural product; Penicillium.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents* / chemistry
  • Fungi
  • Penicillium* / chemistry
  • Polyketides* / chemistry
  • Terpenes / pharmacology

Substances

  • Anti-Infective Agents
  • Polyketides
  • Terpenes