High-dimensional immunophenotyping reveals immune cell aberrations in patients with undiagnosed inflammatory and autoimmune diseases

J Clin Invest. 2023 Dec 15;133(24):e169619. doi: 10.1172/JCI169619.

Authors

Alisa A Mueller¹, Takanori Sasaki¹, Joshua W Keegan², Jennifer P Nguyen², Alec Griffith², Alice M Horisberger¹, Thomas Licata¹, Elizabeth Fieg¹, Ye Cao¹, Mehreen Elahee¹, Kathryne E Marks¹, Daimon P Simmons^{1

3}, Lauren C Briere⁴, Laurel A Cobban¹, J Carl Pallais¹, Frances A High⁵, Melissa A Walker⁶, Jenny J Linnoila⁶, Jeffrey A Sparks¹, V Michael Holers⁷, Karen H Costenbader¹; Undiagnosed Diseases Network; David A Sweetser^{4

5}, Joel B Krier¹, Joseph Loscalzo¹, James A Lederer², Deepak A Rao¹

Affiliations

¹ Department of Medicine.
² Department of Surgery, and.
³ Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
⁴ Center for Genomic Medicine.
⁵ Department of Pediatrics, and.
⁶ Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
⁷ Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

No abstract available

Keywords: Autoimmune diseases; Autoimmunity; Inflammation; Rheumatology.

MeSH terms

Autoimmune Diseases* / diagnosis
Autoimmunity
Humans
Immunophenotyping

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