Identification of the novel HLA allele HLA-DRB1*03:201 by next-generation sequencing

HLA. 2024 Jan;103(1):e15262. doi: 10.1111/tan.15262. Epub 2023 Oct 22.

Abstract

HLA-DRB1*03:201 differs from HLA-DRB1*03:01 in exon 3 at codon 178 resulting in a proline to serine substitution.

Keywords: HLA-DRB1*03:01; HLA-DRB1*03:201; NGS; novel HLA allele.

MeSH terms

  • Alleles
  • Base Sequence
  • Exons / genetics
  • HLA-DRB1 Chains / genetics
  • High-Throughput Nucleotide Sequencing*
  • Humans

Substances

  • HLA-DRB1 Chains