Lymphomas and Amyloid in the Gastrointestinal Tract

Surg Pathol Clin. 2023 Dec;16(4):719-743. doi: 10.1016/j.path.2023.05.008. Epub 2023 Jun 26.

Abstract

Lymphoproliferative disorders are a heterogeneous group of neoplasms with varying clinical, morphologic, immunophenotypic, and genetic characteristics. A subset of lymphomas have a proclivity for the gastrointestinal tract, although this region may also be involved by systemic lymphomas. In addition, a number of indolent lymphoproliferative disorders of the gastrointestinal tract have been defined over the past decade, and it is important to accurately differentiate these neoplasms to ensure that patients receive the proper management. Here, the authors review lymphoid neoplasms that show frequent gastrointestinal involvement and provide updates from the recent hematolymphoid neoplasm classification systems.

Keywords: B-cell lymphoma; Gastrointestinal lymphoma; Lymphoma; Lymphoproliferative disorder; T-cell lymphoma.

Publication types

  • Review

MeSH terms

  • Gastrointestinal Tract / pathology
  • Humans
  • Lymphoma* / diagnosis
  • Lymphoma* / pathology
  • Lymphoproliferative Disorders* / pathology