Analysis of General Toxicity of Ergoferon

Bull Exp Biol Med. 2023 Sep;175(5):644-648. doi: 10.1007/s10517-023-05918-8. Epub 2023 Oct 20.

Abstract

For antibody-based drugs, it is important and relevant to study their toxic effects, which can often become limiting when prescribing this type of therapy. General toxicity of antiviral drug Ergoferon based on technologically processed antibodies was studied on sexually mature animals. Analysis of acute toxicity showed the absence of lethal outcomes when the drug was administered to adult rats at the maximum tolerated doses. In a study of repeated dose toxicity, no adverse effects of the drug were detected.

Keywords: Ergoferon; acute toxicity; chronic toxicity; rats.

MeSH terms

  • Animals
  • Antibodies* / pharmacology
  • Antiviral Agents* / pharmacology
  • Rats
  • Toxicity Tests, Acute

Substances

  • ergoferon
  • Antiviral Agents
  • Antibodies