Increasing hospitalisation of patients with herpes zoster ophthalmicus-an interdisciplinary retrospective analysis

Graefes Arch Clin Exp Ophthalmol. 2024 Feb;262(2):583-588. doi: 10.1007/s00417-023-06277-w. Epub 2023 Oct 20.

Abstract

Background: The occurrence of herpes zoster is rising globally. Future trends will be influenced by changes in population demographics and the growing number of patients at risk. Overall this poses a challenge for healthcare systems.

Methods: In our interdisciplinary, single-centre retrospective analysis, we aimed to assess the burden of the disease within the Department of Dermatology and the Eye Centre from the Medical Centre, University of Freiburg from 2009-2022. We obtained data from 3034 cases coded using the ICD-10 B02.x. Patients were characterised by sex, age, year of treatment, and type of treatment (inpatient vs. outpatient).

Results: Overall we observed a 200% increase in the number of herpes zoster patients over the 13-year period. Upon closer analysis, this was mainly due to a rise in inpatient treatment for herpes zoster ophthalmicus.

Conclusions: If the incidence of herpes zoster ophthalmicus continues to increase at the current rate the number of hospitalisations of zoster ophthalmicus would double by 2040, assuming guideline-appropriate treatment. Overall, the results show a growing need for inpatient ophthalmological care.

Keywords: Chickenpox; Herpes zoster; Herpes zoster ophthalmicus; Vaccination.

MeSH terms

  • Herpes Zoster Ophthalmicus* / diagnosis
  • Herpes Zoster Ophthalmicus* / epidemiology
  • Herpesvirus 3, Human
  • Hospitalization
  • Humans
  • Incidence
  • Retrospective Studies