New forceps free injection technique for delivering descemet membrane endothelial keratoplasty preloaded endothelium-in grafts

Eur J Ophthalmol. 2024 Jan;34(1):287-291. doi: 10.1177/11206721231208998. Epub 2023 Oct 20.

Abstract

Purpose: To describe a new method for delivering DMEK grafts into the recipient's eye with endothelium inward configuration using a no-forceps injection technique.

Methods: We retrospectively review 11 patients that underwent DMEK surgery at our institution using a no-forceps injection technique. The graft was preloaded into an intraocular lens (IOL) cartridge and connected to an anterior chamber maintainer (ACM). A 5 ml non luer lock syringe was inserted into the other end of the ACM to create a one-flow system. The cartridge was inserted into the posterior end of an injector, and the graft was successfully delivered into the recipient's eye.

Result: Twelve eyes of 11 patients were included. Mean follow-up was 9.16 ± 1.3 months. At baseline, mean best corrected visual acuity (BCVA) was 0.76 ± 0.13 logMAr and mean endothelial cell density (ECD) was 2619.00 ± 115.89 cells/mm2. At follow-up, BCVA significantly improved to 0.22 ± 0.05 logMAR (p = 0.003). Although we observed a significant reduction in ECD at follow-up (1688 ± 182.20, p = 0.002), our patients lost only 35.69 ± 6.36% of endothelial cells.

Conclusion: Our technique can help surgeons safely deliver an endothelium-in graft into the recipient's eye. The method doesn't require the use of a forceps, minimizing the risk of endothelial cell loss or graft damage.

Keywords: DMEK; graft injection; kebab technique; surgical management.

MeSH terms

  • Cell Count
  • Descemet Membrane / surgery
  • Descemet Stripping Endothelial Keratoplasty* / methods
  • Endothelial Cells
  • Endothelium, Corneal / transplantation
  • Fuchs' Endothelial Dystrophy* / surgery
  • Humans
  • Retrospective Studies
  • Visual Acuity