Multiple protozoal infections in a single immunocompromised patient: A case report

Trop Parasitol. 2023 Jul-Dec;13(2):121-125. doi: 10.4103/tp.tp_31_21. Epub 2023 Sep 18.

Abstract

Immunocompromised patients with human immunodeficiency virus (HIV) infection are prone to multiple infections, of which parasitic infections are an important cause. Parasitic protozoal infections - both by common and rare protozoa are documented in such patients. Here, we report a rare and interesting case of five protozoal infections affecting a single HIV-infected person at the same time of initial presentation. A 64-years-male came to us with complaints of chronic diarrhea for 6 months. He was investigated and found to be positive for HIV I. His stool examination revealed cysts of Entameba histolytica and Giardia lamblia and oocysts of Cryptosporidium species and Cystoisospora species. His toxoplasma IgG was also positive in high titer. The patient was medically diagnosed and was treated with medications as clinically prescribed - antiretroviral therapy was initiated and he was discharged in due course. A total of five protozoal infections were documented affecting a single person - newly diagnosed immunocompromised male, which by sheer qualitative count of patient case histories, indeed is a rare case reported in the medical literature.

Keywords: Cryptosporidium; Cystoisospora; Entameba histolytica; Giardia lamblia; human immunodeficiency virus; protozoal infection; toxoplasma.