Making the biochemical conversion of lignocellulose more robust

Trends Biotechnol. 2024 Apr;42(4):418-430. doi: 10.1016/j.tibtech.2023.09.014. Epub 2023 Oct 17.

Abstract

Lignocellulose is an alternative to fossil resources, but its biochemical conversion is not economically competitive. While decentralized processing can reduce logistical cost for this feedstock, sugar platforms need to be developed with energy-saving pretreatment technologies and cost-effective cellulases, and products must be selected correctly. Anaerobic fermentation with less energy consumption and lower contamination risk is preferred, particularly for producing biofuels. Great effort has been devoted to producing cellulosic ethanol, but CO2 released with large quantities during ethanol fermentation must be utilized in situ for credit. Unless titer and yield are improved substantially, butanol cannot be produced as an advanced biofuel. Microbial lipids produced through aerobic fermentation with low yield and intensive energy consumption are not affordable as feedstocks for biodiesel production.

Keywords: anaerobic fermentation; decentralized processing; lignocellulose; pretreatment technologies; robust cellulases; sugar platforms.

Publication types

  • Review

MeSH terms

  • Biofuels
  • Butanols
  • Ethanol* / metabolism
  • Fermentation
  • Lignin* / metabolism

Substances

  • lignocellulose
  • Lignin
  • Ethanol
  • Butanols
  • Biofuels