Systematic Assessment of Shock Severity in Postoperative Cardiac Surgery Patients

J Am Coll Cardiol. 2023 Oct 24;82(17):1691-1706. doi: 10.1016/j.jacc.2023.08.031.

Abstract

Background: The Society for Cardiovascular Angiography and Interventions (SCAI) shock classification has been shown to provide robust mortality risk stratification in a variety of cardiovascular patients.

Objectives: This study sought to evaluate the SCAI shock classification in postoperative cardiac surgery intensive care unit (CSICU) patients.

Methods: This study retrospectively analyzed 26,792 postoperative CSICU admissions at a heart center between 2012 and 2022. Patients were classified into SCAI shock stages A to E using electronic health record data. Moreover, the impact of late deterioration (LD) as an additional risk modifier was investigated.

Results: The proportions of patients in SCAI shock stages A to E were 24.4%, 18.8%, 8.4%, 35.5%, and 12.9%, and crude hospital mortality rates were 0.4%, 0.6%, 3.3%, 4.9%, and 30.2%, respectively. Similarly, the prevalence of postoperative complications and organ dysfunction increased across SCAI shock stages. After multivariable adjustment, each higher SCAI shock stage was associated with increased hospital mortality (adjusted OR: 1.26-16.59) compared with SCAI shock stage A, as was LD (adjusted OR: 8.2). The SCAI shock classification demonstrated a strong diagnostic performance for hospital mortality (area under the receiver operating characteristic: 0.84), which noticeably increased when LD was incorporated into the model (area under the receiver operating characteristic: 0.90).

Conclusions: The SCAI shock classification effectively risk-stratifies postoperative CSICU patients for mortality, postoperative complications, and organ dysfunction. Its application could, therefore, be extended to the field of cardiac surgery as a triage tool in postoperative care and as a selection criterion in research.

Keywords: cardiac surgery; cardiogenic shock; cardiovascular; critical care; mortality.

MeSH terms

  • Cardiac Surgical Procedures* / adverse effects
  • Hospital Mortality
  • Humans
  • Intensive Care Units
  • Multiple Organ Failure
  • Postoperative Complications / epidemiology
  • Retrospective Studies
  • Shock*
  • Shock, Cardiogenic / epidemiology
  • Shock, Cardiogenic / etiology