Hypereosinophilic vasculitis with Raynaud phenomenon presentation: a case report

Egypt Heart J. 2023 Oct 18;75(1):89. doi: 10.1186/s43044-023-00418-6.

Abstract

Background: Previous case series have reported idiopathic eosinophilic vasculitis as a potential manifestation of hypereosinophilic syndrome (HES). This condition is characterized by digital necrotizing, systemic vasculitis that affects varying-sized blood vessels. This report presents our experience in treating a patient with eosinophilic vasculitis.

Case presentation: We describe the case of a 23-year-old man who presented with idiopathic HES, which manifested as digital ulcers and peripheral ischemia in both the upper and lower limbs, without the involvement of other organ systems. After ruling out primary and secondary causes of eosinophilia, a diagnosis of HES was established. Our patient has shown a positive response to corticosteroid therapy.

Conclusions: Our case contributes to the existing evidence about diagnosing idiopathic eosinophilic vasculitis in patients with HES. We observed a favorable response to corticosteroid treatment in our patient.

Keywords: Corticosteroid; Eosinophilic disorders; Eosinophilic vasculitis; Hypereosinophilic syndrome; Polyangiitis.