The L-proline modified Zr-based MOF (Basu-proline) catalyst for the one-pot synthesis of dihydropyrano[3,2-c]chromenes

Amin Benrashid; Davood Habibi; Masoumeh Beiranvand; Maryam Mahmoudiani Gilan

doi:10.1038/s41598-023-44774-4

The L-proline modified Zr-based MOF (Basu-proline) catalyst for the one-pot synthesis of dihydropyrano[3,2-c]chromenes

Sci Rep. 2023 Oct 17;13(1):17608. doi: 10.1038/s41598-023-44774-4.

Authors

Amin Benrashid¹, Davood Habibi², Masoumeh Beiranvand¹, Maryam Mahmoudiani Gilan¹

Affiliations

¹ Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Iran.
² Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Iran. davood.habibi@gmail.com.

Abstract

A novel, reusable, and efficient L-proline-modified Zr-based metal-organic framework (Basu-proline) was designed, synthesized, and characterized by Fourier Transform-Infrared spectroscopy (FT-IR), Energy-Dispersive X-ray spectroscopy (EDX), elemental mapping, Field Emission Scanning Electron Microscopy (FE-SEM), X-ray Diffraction analysis (XRD), Thermo-Gravimetric-Differential Thermal Analysis (TGA-DTA), and N₂ adsorption-desorption isotherms. Then, its catalytic performance was assessed in the synthesis of dihydropyrano[3,2-c]chromenes via the one-pot, three-component tandem condensation reaction of 4-hydroxycoumarin, aromatic aldehydes and malononitrile. The Basu-proline catalyst exhibited a better efficiency than some reported protocols regarding higher yields, lower reaction times, and simple separation.