Emotional functioning in long COVID: Comparison to post-concussion syndrome using the Personality Assessment Inventory

Clin Neuropsychol. 2024 May;38(4):963-983. doi: 10.1080/13854046.2023.2264546. Epub 2023 Oct 15.

Abstract

Objective: Recent studies on Long COVID found that patients report prominent emotional distress and significant correlations between distress and cognitive performance have been identified, raising the question of how to manage or treat these issues. To understand psychological functioning in Long COVID further, this study examined personality responses on the Personality Assessment Inventory (PAI) to compare psychological functioning in a Long COVID group with a post-concussion syndrome (PCS) group, a syndrome with a significant psychological component. Participants and methods: Participants included 201 consecutive Long COVID outpatients (Mean age = 48.87 years, mean education = 14.82, 71.6% Female, 82.6% White) and a comparison group of 102 consecutively referred PCS outpatients (Mean age = 46.08, mean education = 14.17, 63.7% Female, 88.2% White). Effect sizes and t-tests were calculated using the PAI validity, clinical, interpersonal, and treatment consideration scales as well as clinical subscales. Results: The results replicated earlier findings on the PAI in Long COVID by demonstrating that both Long COVID and PCS groups had the highest mean elevations on SOM and DEP scales but no statistically significant between group differences in mean scale elevations. Results support similarities in psychological functioning between Long COVID and PCS patients emphasizing the importance of evaluating psychological functioning in neuropsychological evaluations for these populations. Further, results suggest that psychological treatment strategies for PCS patients may be helpful for Long COVID patients, but more research is needed.

Keywords: Long COVID; Personality Assessment Inventory; post-acute sequalae of COVID-19 (PASC); post-concussion syndrome; psychological assessment.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Adult
  • Aged
  • COVID-19* / complications
  • COVID-19* / psychology
  • Emotions / physiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Personality Assessment
  • Post-Acute COVID-19 Syndrome
  • Post-Concussion Syndrome* / diagnosis
  • Post-Concussion Syndrome* / psychology