Vaccines against tick-borne diseases: a big step forward?

Nathalie Boulanger; Stephen Wikel

doi:10.1016/j.pt.2023.10.001

Vaccines against tick-borne diseases: a big step forward?

Trends Parasitol. 2023 Dec;39(12):989-990. doi: 10.1016/j.pt.2023.10.001. Epub 2023 Oct 12.

Authors

Nathalie Boulanger¹, Stephen Wikel²

Affiliations

¹ Fédération de Médecine Translationnelle - UR7290 : Early Bacterial Virulence: Group Borrelia, Université de Strasbourg, France; Centre National de Référence Borrelia, Centre Hospitalier Universitaire, Strasbourg, France. Electronic address: nboulanger@unistra.fr.
² Department of Medical Sciences, Frank H. Netter, M.D., School of Medicine, Quinnipiac University, Hamden, CT 06518, USA. Electronic address: stephen.wikel@quinnipiac.edu.

PMID: 37838513
DOI: 10.1016/j.pt.2023.10.001

Abstract

Ticks and tick-borne diseases are on the rise due to socioecosystemic changes and climate modification and are affecting human and animal health. Few vaccines are available. Two recent articles from Matias et al. and Pine et al. used mRNA technology to explore tick and pathogen proteins as vaccine candidates.

Keywords: Lyme vaccine; acquired resistance; hypersensitivity; tick saliva; transmission-blocking vaccine.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Humans
Tick-Borne Diseases* / prevention & control
Ticks*
Vaccines*

Substances

Vaccines